The 40 S&W caliber closes the gap between the .45 Auto calibers and the 9×19 service calibers. The Glock 22 is now available with Gen5 technologies including the nDLC finish, a flared mag-well, the enhanced Glock Marksman barrel (GMB) for increased accuracy, and an ambidextrous slide stop lever and in MOS configuration.

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GLOCK 22 Gen 5 MOS FS .40 S&W 15RD 4.49” Pistol, Black – PA225S203MOS

Overview

The GLOCK 22 Gen 5 MOS FS .40 S&W is the next evolution of one of the most trusted duty pistols in the world. Chambered in the powerful .40 Smith & Wesson cartridge and built on GLOCK’s Gen 5 platform, this handgun blends modern innovation with proven reliability. The addition of MOS (Modular Optic System) compatibility makes it a true contender in both professional service use and personal defense scenarios. Whether you are in law enforcement, security, or simply a firearms enthusiast seeking a high-performance defensive handgun, the GLOCK 22 Gen 5 MOS delivers exceptional accuracy, rugged durability, and versatile optics-ready capability.

With its 4.49-inch barrel, 15-round magazine, and forward slide serrations, the pistol is optimized for speed, control, and adaptability. The nDLC finish offers superior corrosion resistance, while the improved Gen 5 ergonomics ensure comfort and control under any conditions.

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Key Features & Benefits

• Caliber: .40 S&W – renowned for its balance of stopping power and manageable recoil.

• Capacity: 15+1 rounds for optimal defensive readiness.

• Barrel Length: 4.49 inches – ideal for a duty or home-defense pistol.

• MOS Configuration: Accepts popular pistol optics for faster target acquisition.

• Forward Slide Serrations (FS): Enhanced grip for press checks and slide manipulation.

• GLOCK Marksman Barrel (GMB): Delivers improved accuracy with enhanced rifling.

• Gen 5 Frame: No finger grooves, flared magwell, and ambidextrous slide stop lever.

• nDLC Finish: Extremely durable coating for superior wear and corrosion resistance.

• Safe Action® System: Three independent safety mechanisms for confident carry.

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Performance and Reliability

The GLOCK 22 Gen 5 MOS is engineered for consistent performance in the most demanding conditions. Chambered in .40 S&W, it offers a heavier projectile than 9mm, delivering deeper penetration and greater kinetic energy—qualities valued by many law enforcement agencies worldwide.

The Safe Action® trigger system provides a consistent pull from the first shot to the last, with an integrated trigger safety to prevent accidental discharges. The ambidextrous slide stop lever caters to both right- and left-handed shooters, while the flared magwell ensures faster, more efficient reloads during high-stress situations.

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Optics-Ready MOS Advantage

The MOS (Modular Optic System) allows shooters to mount a variety of popular red dot sights directly to the slide without the need for aftermarket modifications. This feature gives you:

• Faster Target Acquisition: Red dots help you get on target quicker, especially in dynamic shooting environments.

• Improved Accuracy at Range: Optics provide a clearer aiming point for precise shot placement.

• Customization Flexibility: Easily swap optics based on mission or personal preference.

The pistol includes adapter plates for popular optic footprints, ensuring broad compatibility.

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Ergonomic Upgrades in the Gen 5 Platform

The Gen 5 design represents a series of refinements over previous generations:

No Finger Grooves: Allows a more natural grip for shooters of all hand sizes.

Ambidextrous Slide Stop: Enhances control for left-handed shooters and off-hand manipulation.

Flared Magwell: Aids in quick reloads under time pressure.

Enhanced Trigger Feel: Smoother pull for improved shot consistency.

Reversible Magazine Catch: User-configurable for right- or left-handed operation.

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Applications

1.

Law Enforcement Duty Pistol

The GLOCK 22 has been a favorite among police departments for decades due to its balance of firepower and controllability. The Gen 5 MOS edition builds on that legacy, adding the benefits of an optics-ready platform without compromising ruggedness.

2.

Home Defense

With its high capacity, reliable stopping power, and ability to mount optics and lights, the GLOCK 22 Gen 5 MOS is an excellent choice for home protection.

3.

Competitive Shooting

The MOS capability and GLOCK Marksman Barrel make it competitive in IDPA, USPSA, and other shooting sports where speed and accuracy are critical.

4.

Personal Carry (Open or Concealed)

Though full-sized, the pistol’s polymer frame keeps weight manageable for open carry, security work, or concealed carry with the right holster.

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Why Choose the GLOCK 22 Gen 5 MOS Over Other .40 S&W Pistols?

• Proven Law Enforcement Pedigree: The GLOCK 22 has a track record with police and security forces worldwide.

• Versatile Optics Mounting: Few duty pistols offer MOS capability without aftermarket machining.

• Legendary Reliability: GLOCK pistols function in adverse weather, dust, mud, and extreme temperatures.

• Ease of Maintenance: Simple takedown and minimal parts make cleaning fast and straightforward.

• Aftermarket Support: From holsters to triggers to optics, you’ll find no shortage of compatible accessories.

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Maintenance & Care

Proper maintenance ensures the GLOCK 22 Gen 5 MOS remains dependable:

1. Unload and Clear the Firearm – Always check the chamber before cleaning.

2. Field Strip the Pistol – Simple takedown requires no special tools.

3. Clean the Barrel – Use the included brush and cleaning rod to remove fouling.

4. Lubricate Contact Points – Keep the slide rails, barrel hood, and locking block lightly oiled.

5. Reassemble & Function Check – Ensure smooth operation before storage.

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Final Thoughts

The GLOCK 22 Gen 5 MOS FS .40 S&W 15RD 4.49” Pistol is the ultimate evolution of GLOCK’s most trusted duty handgun. By pairing the raw power of the .40 Smith & Wesson cartridge with modern enhancements like the Modular Optic System, forward slide serrations, and Gen 5 ergonomics, this pistol stands ready for any mission. Whether for professional service, home defense, or competitive shooting, the GLOCK 22 Gen 5 MOS offers a blend of firepower, adaptability, and battle-tested reliability that is hard to match.glock 22

If you want a pistol that’s tough enough for the battlefield, precise enough for competition, and reliable enough to defend your home, the GLOCK 22 Gen 5 MOS FS should be at the top of your list.

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